Article
Quantitative trait locus analysis of susceptibility to diet-induced atherosclerosis in recombinant inbred mice.
Biochemical genetics - 1 Dec 1994
Hyman R W, Frank S, Warden C H, Daluiski A, Heller R, Lusis A J
Abstract excerpt
Quantitative trait locus (QTL) analysis is a statistical method that can be applied to identify loci making a significant impact on a phenotype. For the phenotype of susceptibility to diet-induced atherosclerosis in the mouse, we have studied four quantitative traits: area of aortic fatty streaks...
Topics
- Animals
- Apolipoprotein A-I
- Apolipoprotein A-II
- Arteriosclerosis
- Cholesterol
- Cholesterol, HDL
- Cholesterol, VLDL
- Diet, Atherogenic
- Genetic Predisposition to Disease
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Phenotype
- Probability
- Recombination, Genetic
- Species Specificity