Article
Quantitative trait locus analysis of susceptibility to diet-induced atherosclerosis in recombinant inbred mice.
Biochemical genetics - 1 Dec 1994
Hyman R W, Frank S, Warden C H, Daluiski A, Heller R, Lusis A J
Abstract excerpt
Quantitative trait locus (QTL) analysis is a statistical method that can be applied to identify loci making a significant impact on a phenotype. For the phenotype of susceptibility to diet-induced atherosclerosis in the mouse, we have studied four quantitative traits: area of aortic fatty streaks and serum concentrations of high-density lipoprotein-bound cholesterol (HDL-cholesterol), apolipoprotein A-I, and...
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