Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse.

doi:10.1093/ajcn/62.2.458S

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse.

The American journal of clinical nutrition - 1 Aug 1995

Paigen B

Abstract excerpt

The natural variation among inbred strains of mice was used to elucidate the genetic factors underlying the responsiveness to high-fat and high-cholesterol diets. The nine strains examined are the progenitors of recombinant inbred strain sets: C57BL/6J, C57L/J, SWR/J, SJL/J, SM/J, A/J, AKR/J, C3H/HeJ, and DBA/2J. Plasma lipids, liver lipids, the prevalence of cholesterol gallstones, and the size of aortic fatty...

Topics

Animals
Arteriosclerosis
Cholelithiasis
Cholesterol, Dietary
Dietary Fats
Disease Models, Animal
Disease Susceptibility
Dose-Response Relationship, Drug
Female
Genetic Variation
Lipid Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipids

Liver

Mice

Mice, Inbred AKR

Mice, Inbred C3H

Mice, Inbred C57BL

Mice, Inbred DBA

Source

Open in PubMed

Identifiers

PMID: 7625360
DOI: 10.1093/ajcn/62.2.458S

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7625360-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse.PMID 7625360Read ↗

Hyper- and hypo-responsiveness to dietary fat and cholesterol among inbred mice: searching for level and variability genes.Semantic proximity Read ↗

Complex genetic control of HDL levels in mice in response to an atherogenic diet. Coordinate regulation of HDL levels and bile acid metabolism.Semantic proximity Read ↗

Effects of atherogenic diet on hepatic gene expression across mouse strainsSemantic proximity Read ↗

Phenotypic characterization of the Ath-1 gene controlling high density lipoprotein levels and susceptibility to atherosclerosis.Semantic proximity Read ↗

Atherosclerosis susceptibility Loci identified in an extremely atherosclerosis-resistant mouse strain.Semantic proximity Read ↗

Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice.Semantic proximity Read ↗

Regional Variation in Genetic Control of Atherosclerosis in Hyperlipidemic Mice.Semantic proximity Read ↗

Quantitative trait loci analysis for plasma HDL-cholesterol concentrations and atherosclerosis susceptibility between inbred mouse strains C57BL/6J and 129S1/SvImJ.Semantic proximity Read ↗

Using inbred mouse strains to identify genes for complex diseases.Semantic proximity Read ↗

Fine Mapping of the Mouse Ath28 Locus Yields Three Atherosclerosis Modifying Sub-Regions.Semantic proximity Read ↗

QTL mapping for genetic determinants of lipoprotein cholesterol levels in combined crosses of inbred mouse strains.Semantic proximity Read ↗

A locus conferring resistance to diet-induced hypercholesterolemia and atherosclerosis on mouse chromosome 2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.