Article
p53 and Ki-ras as prognostic factors for Dukes' stage B colorectal cancer.
European journal of cancer (Oxford, England : 1990) - 1 May 2000
Bouzourene H, Gervaz P, Cerottini J P, Benhattar J, Chaubert P, Saraga E, Pampallona S, Bosman F T, Givel J C
Abstract excerpt
Mutations of the TP53 and Ki-ras genes have been reported to be of prognostic importance in colorectal carcinomas. An increased intracellular concentration of the p53 protein, although not identical to, is sometimes seen in tumours with TP53 mutation and has been correlated with poor prognosis in some tumour types. Previous colorectal cancer studies, addressing the prognostic importance of Ki-ras mutation and...
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