p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy.

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Article

p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy.

Blood - 1 Jan 1993

Neri A, Baldini L, Trecca D, Cro L, Polli E, Maiolo A T

Abstract excerpt

The frequency and type of p53 gene mutations was investigated in a series of 52 cases of multiple myeloma (MM) representative of the different clinical phases and forms of the disease (indolent, 12 cases; chronic, 24 cases; acute/leukemic, 16 cases). DNAs were analyzed for p53 gene mutations in e...

Topics

Adult
Aged
Aged, 80 and over
Base Sequence
Blotting, Southern
Exons
Female
Genes, p53
Humans
Male
Middle Aged
Molecular Sequence Data
Multiple Myeloma
Mutation
Nucleic Acid Conformation
Point Mutation
Polymerase Chain Reaction
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 8417784

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8417784-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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