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Article

Extracellular matrix regulates expression of the TGF-beta 1 gene.

1 Jan 1993

Abstract excerpt

Transforming growth factor-beta (TGF-beta) is a potent regulator of cell proliferation and modulates the interactions of cells with their extracellular matrix (ECM), in part by inducing the synthesis of various ECM proteins. Three different isoforms of TGF-beta are synthesized in a defined pattern in specific cell populations in vivo. In the specific case of TGF-beta 1, this well-defined and limited expression...

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PMID: 8416992
DOI: 10.1083/jcb.120.1.253

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Source receipt: pubmed, retrieved 7 Sept 2026.

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