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Article

The Effect of TGF-β on Keloid Fibroblast Proliferation and Collagen Synthesis

1 Oct 1996

Abstract excerpt

Keloids are characterized by an overabundant deposition of collagen, and they recur frequently following excision. Fibroblasts isolated from keloid tissue and maintained in cell culture continue to express an increased capacity to produce collagen. In an effort to define the mechanisms responsible for keloid formation, the potential of exogenous transforming growth factor beta 1 (TGF-beta 1) to differentially...

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PMID: 8823022
DOI: 10.1097/00006534-199610000-00012

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