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Article

Malignant mammary cells acquire independence from extracellular context for regulation of estrogen receptor alpha.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jan 2004

Novaro Virginia, Radisky Derek C, Ramos Castro Nancy E, Weisz Alessandro, Bissell Mina J

Abstract excerpt

Interactions between luminal epithelial cells and their surrounding microenvironment govern the normal development and function of the mammary gland. Alterations of these interactions can induce abnormal intracellular signaling pathways that affect the development and progression of breast tumors. One critical component of mammary gland development, as well as breast cancer progression, is the expression of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

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Identifiers

PMID: 14734499
DOI: 10.1158/1078-0432.ccr-031209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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