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Article

Relationships between mesangial cell proliferation and types I and IV collagen mRNA levels in vitro.

The American journal of physiology - 1 Sept 1995

He C J, Striker L J, Tsokos M, Yang C W, Peten E P, Striker G E

Abstract excerpt

Changes in the composition of the mesangial extracellular matrix (ECM) and cell turnover are present in glomerular disease. To determine if ECM changes play a role in perpetuating mesangial cell dysfunction, we examined a line of mouse mesangial cells cultured on films or gels of several ECM components and also on methyl cellulose, an inert substrate that prevents attachment. Cells on films of fibronectin or type...

Topics

Animals
Cell Adhesion
Cell Count
Cell Division
Cells, Cultured
Collagen
Extracellular Space
Fluorescent Antibody Technique
Glomerular Mesangium
Mice
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Messenger

Substrate Specificity

Thymidine

Source

Identifiers

PMID: 7573384
DOI: 10.1152/ajpcell.1995.269.3.C554

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7573384-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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