Article
Identification through overexpression and tagging of the variant type of the mouse H1e and H1c genes.
The Journal of biological chemistry - 5 Jan 1993
Brown D T, Sittman D B
Abstract excerpt
Multiple, nonallelic forms of histone H1 are found in most mammalian tissues. Attempts to determine a functional significance to this diversity is hindered by a paucity of primary amino acid sequence data. Although numerous H1 genes have been cloned, the type of variant they encode cannot be dete...
Topics
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromatography, High Pressure Liquid
- Cloning, Molecular
- Electrophoresis, Polyacrylamide Gel
- Gene Expression
- Genetic Variation
- Histones
- Leukemia, Erythroblastic, Acute
- Methionine
- Mice
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oligodeoxyribonucleotides
- Plasmids
- Polymerase Chain Reaction