Article
Histone H1 overexpressed to high level in tobacco affects certain developmental programs but has limited effect on basal cellular functions.
Proceedings of the National Academy of Sciences of the United States of America - 17 Sept 1996
Prymakowska-Bosak M, Przewłoka M R, Iwkiewicz J, Egierszdorff S, Kuraś M, Chaubet N, Gigot C, Spiker S, Jerzmanowski A
Abstract excerpt
Histone H1, a major structural component of chromatin fiber, is believed to act as a general repressor of transcription. To investigate in vivo the role of this protein in transcription regulation during development of a multicellular organism, we made transgenic tobacco plants that overexpress the gene for Arabidopsis histone H1. In all plants that overexpressed H1 the total H1-to-DNA ratio in chromatin...
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