Article
Histopathogenesis of malignant skin melanoma induced in genetically susceptible transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1993
Mintz B, Silvers W K, Klein-Szanto A J
Abstract excerpt
Animal models of human malignant skin melanoma were created in melanoma-susceptible inbred-strain transgenic mice by grafting skin from donors of high-susceptibility lines to hosts of a low-susceptibility line, thereby overcoming the problem of early death of the more susceptible animals from eye...
Topics
- Animals
- Female
- Genetic Predisposition to Disease
- Male
- Melanocytes
- Melanoma, Experimental
- Mice
- Mice, Transgenic
- Skin
- Skin Neoplasms
- Skin Transplantation