Article
Molecular biology of malignant melanoma.
Advances in experimental medicine and biology - 1 Jan 2008
Pons Mar, Mancheño-Corvo Pablo, Martín-Duque Pilar, Quintanilla Miguel
Abstract excerpt
The incidence of melanoma has increased more rapidly than any other type of cancer. In this review, we summarize the most important genetic alterations that contribute to the development of malignant melanoma. Our knowledge of the genetic and biological events involved in the genesis and progression of this disease has been benefited from the evolvement of a wealth of genetically engineered animal models....
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