Article
Preferential cis action of IS10 transposase depends upon its mode of synthesis.
Molecular microbiology - 1 Jul 1993
Jain C, Kleckner N
Abstract excerpt
A number of bacterial DNA-binding proteins, including IS element transposases, act preferentially in cis. We show below that the degree of preferential cis action by IS10 transposase depends upon its mode of synthesis at steps subsequent to transcription initiation. Cis preference is increased several fold by mutations that decrease translation initiation, by the presence of IS10-specific antisense RNA and by...
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