Article
IS10 antisense control in vivo is affected by mutations throughout the region of complementarity between the interacting RNAs.
Journal of molecular biology - 10 Mar 1995
Jain C
Abstract excerpt
Translation of the IS10 transposase mRNA (RNA-IN) is inhibited by antisense pairing with a small IS10 encoded transcript called RNA-OUT. To further characterize IS10 antisense control, an extensive set of mutations in the region of complementarity between RNA-OUT, and its target RNA-IN have been isolated. These mutations have been characterized for their effects on antisense inhibition of transposase gene...
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