Article
Evidence for programmed cell death of self-reactive gamma delta T cell receptor-positive thymocytes.
European journal of immunology - 1 Oct 1993
Dent A L, Matis L A, Bluestone J A, Hedrick S M
Abstract excerpt
The negative selection of T cells expressing the gamma delta T cell antigen receptor (gamma delta T cells) was studied using transgenic mice expressing a gamma delta receptor with specificity for an H-2T-linked class I major histocompatibility complex molecule from H-2b mice. The potentially self...
Topics
- Animals
- Apoptosis
- Autoimmunity
- H-2 Antigens
- Histocompatibility Antigen H-2D
- In Vitro Techniques
- Lymphocyte Activation
- Mice
- Mice, Transgenic
- Models, Biological
- Phenotype
- Receptors, Antigen, T-Cell, gamma-delta
- Spleen
- T-Lymphocyte Subsets