Article
Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineage.
The Journal of experimental medicine - 1 Apr 1993
Wells F B, Tatsumi Y, Bluestone J A, Hedrick S M, Allison J P, Matis L A
Abstract excerpt
Recent evidence suggests that T cells expressing gamma/delta antigen receptors (T cell receptor [TCR]) are subject to positive selection during development. We have shown that T cells expressing a class I major histocompatibility complex (MHC)-specific gamma/delta TCR transgene (tg) are not posit...
Topics
- Animals
- Cell Differentiation
- Cyclosporine
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Transgenic
- Phenotype
- Receptors, Antigen, T-Cell, gamma-delta
- Signal Transduction
- T-Lymphocytes
- Thymus Gland