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Article

TCR analysis reveals significant repertoire selection during in vitro lymphocyte culture

1 Aug 1997

Abstract excerpt

The in vitro stimulation of T lymphocytes is frequently used as a technique to expand specific cells present at low precursor frequency in vivo. However, cells analysed after such procedures may no longer reflect those originally present in vivo because of the variable efficiency of outgrowth of different T cell subpopulations. To systematically assess this and to complement functional assays, we have analysed...

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Identifiers

PMID: 9263004
DOI: 10.1093/intimm/9.8.1073

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