Article
Selective usage of TCR V beta in tumor-specific CTL lines isolated from ovarian tumor-associated lymphocytes.
Anticancer research - 1 Jan 2000
Ioannides C G, Freedman R S
Abstract excerpt
We have developed a series of six CTL lines exhibiting preferential killing of autologous tumour cells from tumour-associated lymphocytes (TALs) infiltrating malignant ovarian ascites. Five out of six CTL lines showed increased percentages of V beta 8.1+ cells, four showed increased percentages o...
Topics
- Cell Line
- Epitopes
- Female
- HLA-A Antigens
- HLA-B Antigens
- Humans
- Lymphocytes, Tumor-Infiltrating
- Ovarian Neoplasms
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta
