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Article

Dominant rearrangements among human tumor-infiltrating lymphocytes. Analysis of T-cells derived from 32 patients with melanoma, lung, and renal cell carcinoma.

Cancer - 1 May 1992

Bennett W T, Pandolfi F, Grove B H, Hawes G E, Boyle L A, Kradin R L, Kurnick J T

Abstract excerpt

Dominant rearrangements of T-cell receptor (TCR) beta-chain genes are reported among tumor-infiltrating lymphocytes (TIL). After interleukin-2 expansion of TIL from renal and lung carcinoma and melanoma biopsy tissues, rearrangements of TCR beta-chain genes were analyzed by Southern blotting. Nongermline restriction fragments, indicating dominant rearrangements, were detected among the TIL from all 6 patients...

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Source

Identifiers

PMID: 1314129
DOI: 10.1002/1097-0142(19920501)69:9<2379::aid-cncr2820690928>3.0.co;2-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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