Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An authentic 3' noncoding region is necessary for efficient poliovirus replication.

Journal of virology - 1 Sept 2005

Brown David M, Cornell Christopher T, Tran Genevieve P, Nguyen Joseph H C, Semler Bert L

Abstract excerpt

Picornavirus RNA replication involves the specific synthesis of negative-strand intermediates followed by an accumulation of positive-strand viral RNA in the presence of a multitude of cellular mRNAs. Previously, in an effort to identify cis-acting elements required for initiation of negative-strand RNA synthesis, we deleted the entire 3' noncoding regions from human rhinovirus and poliovirus genomic RNAs. These...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA, Complementary
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kinetics

Share to Molecular Sequence Data

Share to Mutation

Share to Phenotype

Share to RNA, Viral

Source

Open in PubMed Open full text

Identifiers

PMID: 16140772
DOI: 10.1128/JVI.79.18.11962-11973.2005
PMCID: PMC1212627

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An authentic 3' noncoding region is necessary for efficient poliovirus replication.PMID 16140772Read ↗

An RNA hairpin at the extreme 5' end of the poliovirus RNA genome modulates viral translation in human cells.Semantic proximity Read ↗

Capsid coding sequence is required for efficient replication of human rhinovirus 14 RNASemantic proximity Read ↗

The rhinovirus type 14 genome contains an internally located RNA structure that is required for viral replicationSemantic proximity Read ↗

Deletion or substitution of the aphthovirus 3′ NCR abrogates infectivity and virus replicationSemantic proximity Read ↗

A coding RNA sequence acts as a replication signal in cardiovirusesSemantic proximity Read ↗

Coronavirus Replication: Genomes, Subgenomic RNAs, and Defective Viral GenomesSemantic proximity Read ↗

Functional and genetic plasticities of the poliovirus genome: quasi-infectious RNAs modified in the 5'-untranslated region yield a variety of pseudorevertants.Semantic proximity Read ↗

Mutations in the 5' trailer region of a respiratory syncytial virus minigenome which limit RNA replication to one step.Semantic proximity Read ↗

Pyrimidine-rich region mutations compensate for a stem-loop V lesion in the 5' noncoding region of poliovirus genomic RNA.Semantic proximity Read ↗

Generation of Infectious Poliovirus with Altered Genetic Information from Cloned cDNA.Semantic proximity Read ↗

Similar interactions of the poliovirus and rhinovirus 3D polymerases with the 3' untranslated region of rhinovirus 14.Semantic proximity Read ↗

Minimum internal ribosome entry site required for poliovirus infectivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.