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Article

Genetic variation in vivo and proposed functional domains of the 5' noncoding region of poliovirus RNA.

Journal of virology - 1 Sept 1992

Pöyry T, Kinnunen L, Hovi T

Abstract excerpt

Poliovirus has a single-stranded RNA genome of about 7,440 nucleotides (nt) with an unusually long 750-nt noncoding region in the 5' end (5'NCR). Several regulatory functions have been assigned to the 5'NCR. We sequenced the 5'NCRs of 33 wild-type 3 poliovirus strains to study the range and distribution of naturally occurring sequence variations. In this regard, the 5'NCR can be divided into a conserved part (nt...

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Identifiers

PMID: 1323698
DOI: 10.1128/JVI.66.9.5313-5319.1992
PMCID: PMC289086

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