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Article

Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport.

The EMBO journal - 1 Jul 1993

Townsley F M, Wilson D W, Pelham H R

Abstract excerpt

The KDEL receptor is a seven-transmembrane-domain protein that is responsible for the retrieval of endoplasmic reticulum (ER) proteins from the Golgi complex. It is a temporary resident of the Golgi apparatus: upon binding a KDEL-containing ligand, it moves to the ER, where the ligand is released...

Topics

Amino Acid Sequence
Animals
Binding Sites
Biological Transport
Cells, Cultured
Cytoplasm
DNA Mutational Analysis
Endoplasmic Reticulum
Golgi Apparatus
Humans
Ligands
Membrane Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Protein Conformation

Receptors, Cell Surface

Receptors, Peptide

Source

Open in PubMed Open full text

Identifiers

PMID: 8392934
DOI: 10.1002/j.1460-2075.1993.tb05943.x
PMCID: PMC413532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8392934-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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