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Article

Understanding single-pass transmembrane receptor signaling from a structural viewpoint-what are we missing?

The FEBS journal - 1 Dec 2016

Bugge Katrine, Lindorff-Larsen Kresten, Kragelund Birthe B

Abstract excerpt

Single-pass transmembrane receptors are involved in essential processes of both physiological and pathological nature and represent more than 1300 proteins in the human genome. Despite the high biological relevance of these receptors, the mechanisms of the signal transductions they facilitate are incompletely understood. One major obstacle is the lack of structures of the transmembrane domains that connect the...

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PMID: 27350538
DOI: 10.1111/febs.13793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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