Article
The retrieval function of the KDEL receptor requires PKA phosphorylation of its C-terminus.
Molecular biology of the cell - 1 Oct 2003
Cabrera Margarita, Muñiz Manuel, Hidalgo Josefina, Vega Lucia, Martín María Esther, Velasco Angel
Abstract excerpt
The KDEL receptor is a Golgi/intermediate compartment-located integral membrane protein that carries out the retrieval of escaped ER proteins bearing a C-terminal KDEL sequence. This occurs throughout retrograde traffic mediated by COPI-coated transport carriers. The role of the C-terminal cytoplasmic domain of the KDEL receptor in this process has been investigated. Deletion of this domain did not affect...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.