Article
Detection of the ryanodine receptor mutation associated with malignant hyperthermia in purebred swine populations.
Journal of animal science - 1 Jun 1993
Houde A, Pommier S A, Roy R
Abstract excerpt
A restriction endonuclease assay (REA) that reveals a C/T transition in the ryanodine receptor gene (ryr-1 locus) was proposed to test swine for malignant hyperthermia. The REA was tested in a heterologous pig population of 1,227 individuals representing Hampshire, Duroc, Landrace, and Yorkshire...
Topics
- Alleles
- Animals
- Base Sequence
- Breeding
- Calcium Channels
- DNA
- Gene Frequency
- Genotype
- Halothane
- Haplotypes
- Heterozygote
- Malignant Hyperthermia
- Molecular Sequence Data
- Muscle Proteins
- Mutation
- Polymerase Chain Reaction
- Restriction Mapping
- Ryanodine Receptor Calcium Release Channel