Article
Detection of the ryanodine receptor mutation associated with malignant hyperthermia in purebred swine populations.
Journal of animal science - 1 Jun 1993
Houde A, Pommier S A, Roy R
Abstract excerpt
A restriction endonuclease assay (REA) that reveals a C/T transition in the ryanodine receptor gene (ryr-1 locus) was proposed to test swine for malignant hyperthermia. The REA was tested in a heterologous pig population of 1,227 individuals representing Hampshire, Duroc, Landrace, and Yorkshire breeds. Of this group, 713 pigs had been classified on the basis of the halothane challenge and progeny testing into...
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