Article
Co-segregation of the malignant hyperthermia and the Arg615-Cys615 mutation in the skeletal muscle calcium release channel protein in five European Landrace and Pietrain pig breeds.
Animal genetics - 1 Jun 1994
Vögeli P, Bolt R, Fries R, Stranzinger G
Abstract excerpt
A total of 392 pigs of European Landrace and Pietrain origin segregating for malignant hyperthermia (MH) were genotyped using a polymerase chain reaction (PCR)/restriction endonuclease test for the C-T mutation at nucleotide (nt) 1843 in the skeletal muscle ryanodine receptor (RYR1) gene, earlier...
Topics
- Alleles
- Animals
- Base Sequence
- Calcium Channels
- DNA Primers
- DNA, Satellite
- Europe
- Female
- Genotype
- Halothane
- Haplotypes
- Male
- Malignant Hyperthermia
- Molecular Sequence Data
- Muscle Proteins
- Point Mutation
- Polymorphism, Genetic
- Ryanodine Receptor Calcium Release Channel