Phenotypes associated with malignant hyperthermia susceptibility in swine genotyped as homozygous or heterozygous for the ryanodine receptor mutation.

doi:10.1093/bja/71.3.410

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Article

Phenotypes associated with malignant hyperthermia susceptibility in swine genotyped as homozygous or heterozygous for the ryanodine receptor mutation.

British journal of anaesthesia - 1 Sept 1993

Fletcher J E, Calvo P A, Rosenberg H

Abstract excerpt

We have examined the phenotypic expression of several parameters associated with malignant hyperthermia (MH) susceptibility in three groups (homozygous normal, homozygous abnormal and heterozygous) of Yorkshire/Duroc swine genotyped by a mutation in the ryanodine receptor. Subgroups of homozygous...

Topics

Animals
Base Sequence
Calcium
Calcium Channels
Disease Susceptibility
Genotype
Halothane
Heterozygote
Homozygote
In Vitro Techniques
Malignant Hyperthermia
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Muscle Contraction

Muscle Proteins

Mutation

Phenotype

Ryanodine Receptor Calcium Release Channel

Sarcoplasmic Reticulum

Source

Open in PubMed

Identifiers

PMID: 8398525
DOI: 10.1093/bja/71.3.410

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8398525-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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