The use of restriction landmark genomic scanning to scan the mouse genome for endogenous loci with imprinted patterns of methylation.

doi:10.1002/elps.1150160136

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Article

The use of restriction landmark genomic scanning to scan the mouse genome for endogenous loci with imprinted patterns of methylation.

Electrophoresis - 1 Feb 1995

Shibata H, Yoshino K, Muramatsu M, Plass C, Chapman V M, Hayashizaki Y

Abstract excerpt

Restriction landmark genomic scanning (RLGS) has been used to screen endogenous loci for imprinted patterns of methylation. The screening method is based upon the identification of genetic variation in RLGS profiles between different strains and determining whether specific variant landmarks are transmitted equally to the progeny of reciprocal F1 matings. The RLGS profiles of C57BL/6 (B6) and DBA/2 (D2) and their...

Topics

Alleles
Animals
Chromosome Mapping
Cloning, Molecular
Crosses, Genetic
DNA
DNA Restriction Enzymes
Electrophoresis
Female
Genetic Techniques
Genome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genomic Imprinting

Male

Methylation

Mice

Mice, Inbred C57BL

Mice, Inbred DBA

Pedigree

Source

Open in PubMed

Identifiers

PMID: 7774561
DOI: 10.1002/elps.1150160136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7774561-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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