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Article

Meiosis-specific arrest revealed in DNA topoisomerase II mutants.

Molecular and cellular biology - 1 Jun 1993

Rose D, Holm C

Abstract excerpt

Although the processes of mitosis and meiosis are similar, there is evidence for fundamental regulatory differences between the two. To examine these differences, we have compared the meiotic phenotype of DNA topoisomerase II mutants with their previously described mitotic phenotype (C. Holm, T. Goto, J. Wang, and D. Botstein, Cell 41:553-563, 1985). top2 mutants in meiosis show no defects in the latest...

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Identifiers

PMID: 8388537
DOI: 10.1128/mcb.13.6.3445-3455.1993
PMCID: PMC359813

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