Genetic analysis of chromosome pairing, recombination, and cell cycle control during first meiotic prophase in mammals.

doi:10.1210/er.2005-0017

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Article

Genetic analysis of chromosome pairing, recombination, and cell cycle control during first meiotic prophase in mammals.

Endocrine reviews - 1 Jun 2006

Cohen P E, Pollack S E, Pollard J W

Abstract excerpt

Meiosis is a double-division process that is preceded by only one DNA replication event to produce haploid gametes. The defining event in meiosis is prophase I, during which chromosome pairs locate each other, become physically connected, and exchange genetic information. Although many aspects of this process have been elucidated in lower organisms, there has been scant information available until now about the...

Topics

Animals
BRCA1 Protein
Cell Cycle Proteins
Chromosome Pairing
DNA Helicases
DNA Repair
DNA Repair-Deficiency Disorders
Humans
Meiotic Prophase I
Mutation
Recombination, Genetic

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Open in PubMed

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PMID: 16543383
DOI: 10.1210/er.2005-0017

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