Segregation of recombined chromosomes in meiosis I requires DNA topoisomerase II.

doi:10.1016/0092-8674(90)90349-j

Back to search

Article

Segregation of recombined chromosomes in meiosis I requires DNA topoisomerase II.

Cell - 23 Mar 1990

Rose D, Thomas W, Holm C

Abstract excerpt

To understand better the similarities and differences between meiosis and mitosis, we examined the meiotic role of DNA topoisomerase II, an enzyme that is required mitotically to disentangle sister chromatids at the time of chromosome segregation. In meiosis, we found that topoisomerase II is req...

Topics

Cell Nucleus
Chromosomes, Fungal
DNA Replication
DNA Topoisomerases, Type II
Meiosis
Mutation
Recombination, Genetic
Saccharomyces cerevisiae
Spores, Fungal
Temperature

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.