Article
Failure to detect Epstein-Barr virus DNA in peripheral blood mononuclear cells of most patients with large granular lymphocyte leukemia.
Blood - 15 May 1993
Loughran T P, Zambello R, Ashley R, Guderian J, Pellenz M, Semenzato G, Starkebaum G
Abstract excerpt
Clonal disease of large granular lymphocytes (LGLs) may arise from either CD3+ LGLs (LGL leukemia) or CD3- LGLs (natural killer [NK] cell leukemia). Other patients have chronic LGL proliferations that cannot be proven to be clonal (lymphoproliferative disease of granular lymphocytes [LDGL]). It w...
Topics
- Base Sequence
- CD3 Complex
- DNA, Viral
- Herpesvirus 4, Human
- Humans
- Leukemia, Lymphoid
- Molecular Sequence Data
- Monocytes
- Oligodeoxyribonucleotides
- Phenotype
- Polymerase Chain Reaction
- Tumor Cells, Cultured
