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Article

Interaction of the pim1/spi1 mitotic checkpoint with a protein phosphatase.

Molecular biology of the cell - 1 Mar 1993

Matsumoto T, Beach D

Abstract excerpt

Loss of p58pim1, a homolog of human RCC1, results in uncoupling of mitosis from the completion of DNA replication in fission yeast. An extragenic suppressor of a mutant allele of pim1, esp1, has been isolated and characterized. esp1 encodes a predicted product of 305 amino acid residues, which shares 71% identity with budding yeast SIT4, a type2A related protein phosphatase. p58pim1 binds p25spi1, a 25-kd...

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Identifiers

PMID: 8387358
DOI: 10.1091/mbc.4.3.337
PMCID: PMC300931

Genes

RCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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