Article
Interaction of the pim1/spi1 mitotic checkpoint with a protein phosphatase.
Molecular biology of the cell - 1 Mar 1993
Matsumoto T, Beach D
Abstract excerpt
Loss of p58pim1, a homolog of human RCC1, results in uncoupling of mitosis from the completion of DNA replication in fission yeast. An extragenic suppressor of a mutant allele of pim1, esp1, has been isolated and characterized. esp1 encodes a predicted product of 305 amino acid residues, which sh...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Cycle Proteins
- DNA, Fungal
- DNA-Binding Proteins
- GTP Phosphohydrolases
- Genes, Fungal
- Guanine Nucleotide Exchange Factors
- Humans
- Mitosis
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Phosphoprotein Phosphatases
- Schizosaccharomyces
- Suppression, Genetic