Article
Isolation and characterization of fission yeast sns mutants defective at the mitosis-to-interphase transition.
Genetics - 1 Apr 1998
Matynia A, Mueller U, Ong N, Demeter J, Granger A L, Hinata K, Sazer S
Abstract excerpt
pim1-d1ts was previously identified in a visual screen for fission yeast mutants unable to complete the mitosis-to-interphase transition. pim1+ encodes the guanine nucleotide exchange factor (GEF) for the spi1 GTPase. Perturbations of this GTPase system by either mutation or overproduction of its...
Topics
- Alleles
- Amino Acid Sequence
- Epistasis, Genetic
- GTP Phosphohydrolases
- Gene Expression
- Genetic Complementation Test
- Genetic Linkage
- Guanine Nucleotide Exchange Factors
- Interphase
- Mitosis
- Molecular Sequence Data
- Mutation
- Phenotype
- Schizosaccharomyces