Persistent poliovirus infection: establishment and maintenance involve distinct mechanisms.

doi:10.1016/0042-6822(92)90005-a

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Persistent poliovirus infection: establishment and maintenance involve distinct mechanisms.

Virology - 1 Feb 1992

Borzakian S, Couderc T, Barbier Y, Attal G, Pelletier I, Colbère-Garapin F

Abstract excerpt

Mutants of poliovirus (PV) with highly modified biological properties can be selected in vitro in cells of neural origin. Mutations accumulate in the genome of type 1 PV strains selected in human neuroblastoma cells, modifying cell specificity and conferring to the virus the ability to persist in such nonneural cells as HEp-2c (Pelletier et al., Virology 180, 729 1991). With this cell system, we have both parent...

Topics

Animals
Blotting, Northern
Cell Line
Fluorescent Antibody Technique
Fluorometry
Genome, Viral
Humans
Kinetics
Mice
Neuroblastoma
Nucleic Acid Hybridization

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Poliovirus

Temperature

Time Factors

Tumor Cells, Cultured

Virus Replication

Source

Open in PubMed

Identifiers

PMID: 1310176
DOI: 10.1016/0042-6822(92)90005-a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1310176-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Persistent poliovirus infection: establishment and maintenance involve distinct mechanisms.PMID 1310176Read ↗

Characterization of persistent poliovirus mutants selected in human neuroblastoma cells.Semantic proximity Read ↗

Molecular mechanisms of poliovirus persistence: key role of capsid determinants during the establishment phase.Semantic proximity Read ↗

Precise missense and silent point mutations are fixed in the genomes of poliovirus mutants from persistently infected cells.Semantic proximity Read ↗

Measles virus from a long-term persistently infected human T lymphoblastoid cell line, in contrast to the cytocidal parental virus, establishes an immediate persistence in the original cell line.Semantic proximity Read ↗

Persistent paramyxovirus infections: in co-infections the parainfluenza virus type 5 persistent phenotype is dominant over the lytic phenotype.Semantic proximity Read ↗

Persistent poliovirus infection: development of new models with cell lines.Semantic proximity Read ↗

Cells and viruses with mutations affecting viral entry are selected during persistent infections of L cells with mammalian reoviruses.Semantic proximity Read ↗

Poliovirus mutants excreted by a chronically infected hypogammaglobulinemic patient establish persistent infections in human intestinal cells.Semantic proximity Read ↗

Expression of Mutated Poliovirus Receptors in Human Neuroblastoma Cells Persistently Infected with PoliovirusSemantic proximity Read ↗

Mechanisms of establishment of persistent SARS-CoV-infected cellsSemantic proximity Read ↗

Complete cure of persistent virus infections by antiviral siRNAs.Semantic proximity Read ↗

Characterization of Defective Viral RNA Produced during Persistent Infection of Vero Cells with Murray Valley Encephalitis VirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.