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Article

Persistent reovirus infections of L cells select mutations in viral attachment protein sigma1 that alter oligomer stability.

Journal of virology - 1 Oct 1996

Wilson G J, Wetzel J D, Puryear W, Bassel-Duby R, Dermody T S

Abstract excerpt

During maintenance of L-cell cultures persistently infected with reovirus, mutations are selected in viruses and cells. Cells cured of persistent infection support growth of viruses isolated from persistently infected cultures (PI viruses) significantly better than that of wild-type (wt) viruses. In a previous study, the capacity of PI virus strain L/C to grow better than wt strain type 1 Lang (T1L) in cured...

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Identifiers

PMID: 8794294
DOI: 10.1128/JVI.70.10.6598-6606.1996
PMCID: PMC190700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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