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Mutational Signatures in Wild Type Escherichia coli Strains Reveal Predominance of DNA Polymerase Errors.

Genome biology and evolution - 2 Apr 2024

Garushyants Sofya K, Sane Mrudula, Selifanova Maria V, Agashe Deepa, Bazykin Georgii A, Gelfand Mikhail S

Abstract excerpt

While mutational processes operating in the Escherichia coli genome have been revealed by multiple laboratory experiments, the contribution of these processes to accumulation of bacterial polymorphism and evolution in natural environments is unknown. To address this question, we reconstruct signatures of distinct mutational processes from experimental data on E. coli hypermutators, and ask how these processes...

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PMID: 38401265
DOI: 10.1093/gbe/evae035
PMCID: PMC10995721

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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