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Article

The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway.

Cell - 7 Apr 1995

Hou X S, Chou T B, Melnick M B, Perrimon N

Abstract excerpt

Activation of the receptor tyrosine kinase (RTK) torso defines the spatial domains of expression of the transcription factors tailless and huckebein. Previous analyses have demonstrated that Ras1 (p21ras) operates upstream of the D-Raf (Raf1) serine/threonine kinase in this signaling pathway. By using a recently developed technique of germline mosaics, we find that D-Raf can be activated by torso in the complete...

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PMID: 7720074
DOI: 10.1016/0092-8674(95)90371-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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