Article
The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway.
Cell - 7 Apr 1995
Hou X S, Chou T B, Melnick M B, Perrimon N
Abstract excerpt
Activation of the receptor tyrosine kinase (RTK) torso defines the spatial domains of expression of the transcription factors tailless and huckebein. Previous analyses have demonstrated that Ras1 (p21ras) operates upstream of the D-Raf (Raf1) serine/threonine kinase in this signaling pathway. By...
Topics
- Animals
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- Germ-Line Mutation
- Insect Hormones
- Membrane Proteins
- Models, Biological
- Mosaicism
- Phenotype
- Protein Serine-Threonine Kinases
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-raf
- Proto-Oncogene Proteins p21(ras)
- Receptor Protein-Tyrosine Kinases
- Repressor Proteins