Article
The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila.
Developmental biology - 25 Nov 1996
Perkins L A, Johnson M R, Melnick M B, Perrimon N
Abstract excerpt
Corkscrew (csw) encodes a nonreceptor protein tyrosine phosphatase (PTPase) that has been implicated in signaling from the Torso receptor tyrosine kinase (RTK). csw mutations, unlike tor mutations, are associated with zygotic lethality, indicating that Csw plays additional roles during developmen...
Topics
- Alleles
- Animals
- Blastoderm
- Drosophila
- Drosophila Proteins
- Embryo, Nonmammalian
- Female
- Gene Expression Regulation, Developmental
- Male
- Mammals
- Mutagenesis
- Nervous System
- Phenotype
- Protein Tyrosine Phosphatases
- Protein Tyrosine Phosphatases, Non-Receptor
- Receptor Protein-Tyrosine Kinases
- Signal Transduction
- Wings, Animal