Article
Identification of genomic regions that interact with a viable allele of the Drosophila protein tyrosine phosphatase corkscrew.
Genetics - 1 Oct 2000
Firth L, Manchester J, Lorenzen J A, Baron M, Perkins L A
Abstract excerpt
Signaling by receptor tyrosine kinases (RTKs) is critical for a multitude of developmental decisions and processes. Among the molecules known to transduce the RTK-generated signal is the nonreceptor protein tyrosine phosphatase Corkscrew (Csw). Previously, Csw has been demonstrated to function throughout the Drosophila life cycle and, among the RTKs tested, Csw is essential in the Torso, Sevenless, EGF, and...
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