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Article

MHC-linked LMP gene products specifically alter peptidase activities of the proteasome.

Nature - 16 Sept 1993

Driscoll J, Brown M G, Finley D, Monaco J J

Abstract excerpt

Proteasomes are highly conserved macromolecular structures which function as endopeptidases. They are found in the cytoplasm and nucleus of eukaryotic tissues and consist of at least 14 non-identical subunits with molecular masses ranging from approximately 20 to 32K. Proteasomes are essential in the selective degradation of ubiquitinated and certain non-ubiquitinated proteins, acting as the proteolytic core of...

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Identifiers

PMID: 8371781
DOI: 10.1038/365262a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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