Article
Modulation of Saccharomyces cerevisiae DNA double-strand break repair by SRS2 and RAD51.
Genetics - 1 Mar 1995
Milne G T, Ho T, Weaver D T
Abstract excerpt
RAD52 function is required for virtually all DNA double-strand break repair and recombination events in Saccharomyces cerevisiae. To gain greater insight into the mechanism of RAD52-mediated repair, we screened for genes that suppress partially active alleles of RAD52 when mutant or overexpressed. Described here is the isolation of a phenotypic null allele of SRS2 that suppressed multiple alleles of RAD52...
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