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[Functioning and silent regrouped immunoglobulin genes in the hybridoma genome].

Molekuliarnaia biologiia - 1 Jan 2000

Deev S M, Urakov D N, Shiianov P A, Morozov A Iu, Polianovskiĭ O L

Abstract excerpt

Rearranged genes for heavy and light immunoglobulin chains have been studied in the genomes of hybridoma PTF-02 and parent myeloma P3-X63.Ag8.653. The hybridoma was shown to contain three rearranged allelic variants of the heavy chain gene's locus. Gene H2, responsible for the synthesis of the heavy chain of the antibody to transferrin, was transmitted to the hybridoma cell from a lymphocyte. The structure of the...

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PMID: 8361498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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