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Article

Structural repertoire in VH pseudogenes of immunoglobulins: comparison with human germline genes and human amino acid sequences.

Journal of molecular biology - 10 Feb 1995

Vargas-Madrazo E, Almagro J C, Lara-Ochoa F

Abstract excerpt

In the pool of human immunoglobulin VH gene segments, pseudogenes amount to roughly 30% of the total number of genes. Some of them are highly conserved among unrelated individuals. These facts suggest a possible functional role for pseudogenes in the human immune response diversity. This paper intends to provide additional information about the structure of VH pseudogene sequences to evaluate the possible role of...

Topics

Amino Acid Sequence
Animals
Databases, Factual
Genes, Immunoglobulin
Genetic Variation
Humans
Immunoglobulin Heavy Chains
Immunoglobulin Variable Region
Molecular Sequence Data
Protein Structure, Tertiary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pseudogenes

Sequence Alignment

Source

Identifiers

PMID: 7853406
DOI: 10.1006/jmbi.1994.0067

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7853406-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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