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Article

A general strategy to uncover transcription factor properties identifies a new regulator of drug resistance in yeast.

The Journal of biological chemistry - 28 Mar 2003

Hikkel Imrich, Lucau-Danila Ancuta, Delaveau Thierry, Marc Philippe, Devaux Frédéric, Jacq Claude

Abstract excerpt

We demonstrate a genomewide approach to determine the physiological role of a putative transcription factor, Ylr266, identified through yeast genome sequencing program. We constructed activated forms of the zinc finger (Zn(2)Cys(6)) protein Ylr266, and we analyzed the corresponding transcriptomes with DNA microarrays to characterize the up-regulated genes. The direct target genes of Ylr266 were further identified...

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PMID: 12529331
DOI: 10.1074/jbc.M208549200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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