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Article

Loss of APD1 in yeast confers hydroxyurea sensitivity suppressed by Yap1p transcription factor.

Scientific reports - 20 Jan 2015

Tang Hei-Man Vincent, Pan Kewu, Kong Ka-Yiu Edwin, Hu Ligang, Chan Ling-Chim, Siu Kam-Leung, Sun Hongzhe, Wong Chi-Ming, Jin Dong-Yan

Abstract excerpt

Ferredoxins are iron-sulfur proteins that play important roles in electron transport and redox homeostasis. Yeast Apd1p is a novel member of the family of thioredoxin-like ferredoxins. In this study, we characterized the hydroxyurea (HU)-hypersensitive phenotype of apd1Δ cells. HU is an inhibitor...

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Identifiers

PMID: 25600293
DOI: 10.1038/srep07897
PMCID: PMC4298746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25600293-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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