Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans.

Nature - 12 Jul 1990

Greenwald I, Seydoux G

Abstract excerpt

Certain cell fate decisions are specified by cell-cell interactions during the development of the nematode Caenorhabditis elegans. For example, in a wild-type hermaphrodite gonad, two cells, Z1.ppp and Z4.aaa, have the potential to become the anchor cell (AC). Intercellular communication establishes their fates and ensures that only one cell becomes the AC, while the other becomes a ventral uterine precursor cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cell Communication
Share to Genes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Macromolecular Substances

Share to Mutation

Share to Polymerase Chain Reaction

Share to Receptors, Cell Surface

Share to Signal Transduction

Source

Identifiers

PMID: 2164160
DOI: 10.1038/346197a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans.PMID 2164160Read ↗

Genetic and phenotypic studies of hypomorphic lin-12 mutants in Caenorhabditis elegans.Semantic proximity Read ↗

The lin-11 LIM domain transcription factor is necessary for morphogenesis of C. elegans uterine cells.Semantic proximity Read ↗

LIN-12 protein expression and localization during vulval development in C. elegans.Semantic proximity Read ↗

Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats.Semantic proximity Read ↗

Basolateral localization of the Caenorhabditis elegans epidermal growth factor receptor in epithelial cells by the PDZ protein LIN-10.Semantic proximity Read ↗

The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins.Semantic proximity Read ↗

Tissue-specific regulation of the LIM homeobox gene lin-11 during development of the Caenorhabditis elegans egg-laying system.Semantic proximity Read ↗

Enhancers of glp-1, a gene required for cell-signaling in Caenorhabditis elegans, define a set of genes required for germline development.Semantic proximity Read ↗

Two homologous regulatory genes, lin-12 and glp-1, have overlapping functions.Semantic proximity Read ↗

LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans.Semantic proximity Read ↗

The SEL-12 presenilin mediates induction of the Caenorhabditis elegans uterine pi cell fate.Semantic proximity Read ↗

Functional genomic analysis of the let-7 regulatory network in Caenorhabditis elegans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.