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Article

A second complementation class of cholesterol transport mutants with a variant Niemann-Pick type C phenotype.

Journal of lipid research - 1 Oct 1994

Dahl N K, Daunais M A, Liscum L

Abstract excerpt

We previously isolated Chinese Hamster ovary cell mutants that were defective in the intracellular transport of low density lipoprotein (LDL)-derived cholesterol (Dahl, N.K., K.L. Reed, M.A. Daunais, J.R. Faust, and L. Liscum. 1992 J. Biol. Chem. 267: 4889-4896). Several of the mutants exhibited the same biochemical phenotype as classical Niemann-Pick type C (NPC) fibroblasts. Complementation analysis between...

Topics

Animals
Biological Transport
CHO Cells
Cholesterol
Cholesterol, LDL
Cricetinae
Genetic Complementation Test
Genetic Variation
Hydroxycholesterols
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Mutation

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Niemann-Pick Diseases

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PMID: 7852861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7852861-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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