Absence of prohibitin gene mutations in human epithelial ovarian tumors.

doi:10.1006/gyno.1993.1160

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Article

Absence of prohibitin gene mutations in human epithelial ovarian tumors.

Gynecologic oncology - 1 Jul 1993

Cliby W, Sarkar G, Ritland S R, Hartmann L, Podratz K C, Jenkins R B

Abstract excerpt

Multiple loss of heterozygosity (LOH) studies of ovarian cancers have found a high incidence of chromosome 17 loss in these tumors. Several authors have suggested that the region commonly deleted encompasses 17q12-21. In addition, this region has recently been reported to be linked to the familia...

Topics

Base Sequence
Chromosomes, Human, Pair 17
DNA, Neoplasm
Exons
Female
Heterozygote
Humans
Molecular Sequence Data
Mutation
Oligonucleotide Probes
Ovarian Neoplasms
Prohibitins
Proteins
Repressor Proteins

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