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Article

Ovarian cancer risk in Polish BRCA1 mutation carriers is not associated with the prohibitin 3' untranslated region polymorphism.

BMC cancer - 8 Apr 2008

Jakubowska Anna, Gronwald Jacek, Menkiszak Janusz, Górski Bohdan, Huzarski Tomasz, Byrski Tomasz, Benner Axel, Lubiński Jan, Scott Rodney J, Hamann Ute

Abstract excerpt

BACKGROUND: The variable penetrance of ovarian cancer in BRCA1 mutation carriers suggests that other genetic or environmental factors modify disease risk. The C to T transition in the 3' untranslated region of the prohibitin (PHB) gene alters mRNA function and has recently been shown to be associated with hereditary breast cancer risk in Polish women harbouring BRCA1 mutations. METHODS: To investigate whether the...

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Identifiers

PMID: 18397521
DOI: 10.1186/1471-2407-8-90
PMCID: PMC2364631

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ovarian cancer risk in Polish BRCA1 mutation carriers is not associated with the prohibitin 3' untranslated region polymorphism.PMID 18397521Read ↗

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